When 774 patients were treated for 28 days, an external data safety monitoring committee stopped the study early. More effective treatment requires fewer patients and therefore less time.Ĭomparison of Covid-19 vaccines developed by Pfizer, Moderna, Johnson & Johnson This was originally set to enroll 3,000 patients receiving either placebo or the combination of ‘332 and ritonavir, but stopped at different times depending on the method by which the drug was proven to be effective. When Pfizer reported earnings on Tuesday, the company told investors that news about ‘332 might not reach until early next year. Seven of the 385 patients in the placebo group died, and the 389 patients who received the drug did not die.

The drug also reduced the chances of death for the patient. Pfizer’s drug, codenamed PF-07321332 or simply ‘332, reduced hospitalization by 89% compared to placebo when the HIV drug ritonavir was administered within 3 days of the onset of symptoms. Pfizer said in a press release that it plans to make the drug available using a “step-by-step pricing approach” based on national income levels. Manufacturers help make this drug available to less wealthy countries.

Merck has made the Molnupiravir patent available to manufacturers. They were also worried about whether the new pill would be widely available. The pill also prevented death and was given conditional approval on Thursday by the UK’s top medical regulators.Īn outside expert contacted by STAT said Pfizer’s results, published in a press release and not peer-reviewed or submitted to regulatory agencies, are very promising. Merck and partner Ridgeback Therapeutics announced on October 1 that their pill, molnupiravir, reduced hospitalization and death by 50%. Pfizer’s results are the second success of oral tablets that prevent Covid patients from being hospitalized or dying.

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